Pelargonium root (Pelargonium sidoides DC) extract in paediatric patients - food supplement or medicine?
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چکیده
منابع مشابه
The Root Extract of the Medicinal Plant Pelargonium sidoides Is a Potent HIV-1 Attachment Inhibitor
Global HIV-1 treatment would benefit greatly from safe herbal medicines with scientifically validated novel anti-HIV-1 activities. The root extract from the medicinal plant Pelargonium sidoides (PS) is licensed in Germany as the herbal medicine EPs®7630, with numerous clinical trials supporting its safety in humans. Here we provide evidence from multiple cell culture experiments that PS extract...
متن کاملA Case of hepatotoxicity by Pelargonium sidoides
Background Pelargonium sidoides (PS) is an African herbaceous, perennial plant in the geranium family. The root is the medically part used for respiratory problems [1]. The reported pharmacological activities include moderate direct antibacterial and antiviral potencies and immunomodulatory properties. An alcohol extract of PS has become popular in Germany as a treatment for different respirato...
متن کاملBenzopyranones and their sulfate esters from Pelargonium sidoides.
Investigation of the benzopyranones from the roots of PELARGONIUM SIDOIDES led to the identification of 15 benzopyranones, among them the novel compounds 12 and 14. Furthermore, benzopyranones 4 and 15 were detected in PELARGONIUM SIDOIDES for the first time. Structure determinations were performed by one- and two-dimensional NMR spectroscopy. An HPLC system for the discrimination of these benz...
متن کاملImmunostimulating Effects of Pelargonium Reinforme/sidoides Extract (kalobin) on Mice Infected with Prohemistomum Vivax
The immunostimulating effect of Pelargonium reinforme / sidoides extract (Kalobin) against Prohemistomum vivax infection in mice was investigated. Five groups of mice were constructed. The first group was not treated nor infected and considered as control, the second group; control infected, was not treated but orally infected with 150 P. vivax metacercareae. The third, fourth and fifth groups ...
متن کاملThe Pelargonium sidoides Extract EPs 7630 Drives the Innate Immune Defense by Activating Selected MAP Kinase Pathways in Human Monocytes
Pelargonium sidoides is a medical herb and respective extracts are used very frequently for the treatment of respiratory tract infections. However, the effects of Pelargonium sidoides and a special extract prepared from its roots (EPs 7630) on human immune cells are not fully understood. Here we demonstrate that EPs 7630 induced a rapid and dose-dependent production of TNF-α, IL-6, and IL-10 by...
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ژورنال
عنوان ژورنال: Herba Polonica
سال: 2020
ISSN: 2449-8343
DOI: 10.2478/hepo-2020-0009